I've lost (literally) tens of billions of isk in that darn game over a span fo 7 months played over 3 on-and-off years.
NO ISK FOR ME! I always have bad luck choosing corps. Either they're on a losing side of a minor war...or they're on the losing side of a REALLY BIG FUCKING WAR when teh enemy attacks on christmas eve and blows up your capitol and siezes your entire game-long assets then blows it up for SHITS AND GIGGLES! SHITS AND GIGGLES, MAN! THEY'RE BLEW IT UP FOR SHITS...AND GIGGLES! THEY BLEW UP BILLIONS FOR SHITS AND GIGGLES!
Then when you come back some months later and join with a new coalition to face off against bob and SOMEHOW a small MC-BoB fleet of no more than two dozen varied ships and a deathstar pos with a hanger successfully stave off and totally annihilate and obliterate your side's fleet of 7 dreadnaughts, three dozen battleships, and around 30-40 more ships of varried sub-battleship sizes.
*edit* sorry there's more
THEN you return to your homespace only to un into a BoB gatecamp and lose more assets. After being betrayed in ASCN, mugged in an earlier corp, having my buddies in ASCN hightail it to high sec after BoB nuked us over and over, having months of ships and monies blown up in multiple days, etc., etc. (I left around a 6 months-a year ago lol) not even the ub3r graphics update and promised factional warfare can keep me!
I'm, like, the l33t Bill Gates with no money.